A short questionnaire helps identify whether patients on therapy for GERD are experiencing sleep disturbance and might benefit from an adjustment in therapy.
Gastroesophageal reflux disease (GERD) and sleep disturbance are highly prevalent conditions that occur together in many patients. Recent studies have demonstrated that effective treatment of GERD also ameliorates related sleep dysfunction. Proton-pump inhibitors (PPIs) have been demonstrated to improve quality of life, work productivity, and driving acuity (Am J Gastroenterol 2011; 106:421). However, data have been limited to gastroenterology practice settings. In the current primary-care–based, industry-funded, cluster-randomized, open-label study, researchers evaluated the performance of a questionnaire in identifying sleep disturbance in patients being treated for GERD and, secondarily, the efficacy of esomeprazole in improving sleep disturbance.
From 180 primary care centers in Canada, 1388 patients were administered the PPI Acid Suppression Symptom (PASS) test, a validated questionnaire of five questions that identifies…
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